Fig. 5

Tup11 co-localises with Rst2 at gene promoters in glucose-starved conditions. a Overlap of protein-coding genes annotated to Rst2 ChIP-seq peaks in the glucose, sucrose and glucose-starved conditions. b Overlap of protein-coding genes annotated to Tup11 or Rst2 ChIP-seq peaks in the glucose-starved condition. c Overlap of protein-coding genes enriched for Scr1 in glucose or sucrose conditions and protein-coding genes enriched for Tup11 and Rst2 in glucose-starved conditions d GO terms enriched in the subsets of protein-coding genes bound by Rst2 and Tup11 in glucose-starved conditions. e Enrichment profiles of Tup11 and Rst2 in the glucose-starved condition. Solid line indicates the mean while the coloured region indicates a 95% confidence interval. f Genome browser view of Tup11, Rst2 and RNA Pol II^Ser5 ChIP-seq enrichment at the inv1⁺ locus in glucose, sucrose and glucose-starved (Starved) conditions. The black arrows indicate significant regions of Tup11 and Rst2 enrichment. g Heatmap of gene expression in wild type cells grown in glucose, sucrose and glucose-starved conditions for protein-coding and non-coding loci enriched for both Tup11 and Rst2 in glucose-starved conditions. Enriched GO categories and representative genes are shown to the right for specific clusters within the heatmap. Venn diagram P-values calculated using the hypergeometric probability distribution