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Table 2 Comparison of the main characteristics of TSS mapped in S. pyogenes and S. agalactiae

From: Conserved and specific features of Streptococcus pyogenes and Streptococcus agalactiae transcriptional landscapes

  S. agalactiae NEM316 S. pyogenes S119
Genome length 2.21 Mb 1.88 Mb
Number of coding genes (including pseudogenes) 2120 1816
Number of species-specific coding genes 965 661
Total number of TSS 1210 892
Primary TSS 891 741
Coding genes preceded by a primary TSS 42.0% (891/2120) 40.8% (741/1816)
Secondary TSS 36 14
Internal TSS at less than 200 nt from next CDS in similar orientation 26 11
Other internal TSS in sense orientation 165 42
TSS for antisense RNAs 39 43
Intergenic orphan TSS 53 41
  in both species only in GBS only in GAS
orthologous genes with a primary TSS 533 45 39
orthologous genes with a secondary TSS 2 21 9
orthologous genes with an internal promoter 14 92 32
species-specific gene with a primary TSS 313 169
species-specific gene with a secondary TSS 13 3
species-specific gene with an internal TSS 85 7