Fig. 5From: Comparative analysis of the chicken IFITM locus by targeted genome sequencing reveals evolution of the locus and positive selection in IFITM1 and IFITM3Multiple sequence alignment of the chIFITM proteins showing the mutations across the samples. Amino acid sequence containing the chIFITM1,2,3 SNVs were aligned using Clustal Omega. IM1/2: intramembrane domain 1 and 2, CIL: conserved intracellular loop, *: silent SNVs. Red triangle: INDELs. Red circles highlight codons under positive selection, black circles codons under negative selection (Refer to Additional file 1: Table S4 for more details), black box: conserved localization signal, star: conserved lysine residues; yellow highlight: conserved double cysteine motif (CC)Back to article page