The identification of differentially expressed genes between extremes of placental efficiency in maternal line gilts on day 95 of gestation

Table 3 Gene Ontology Enrichment Analysis

Ontology^a	Category	GO Term	No. DEG in Category	No. in Category	FDR P-value	Gene Symbol^b
MF	GO:0008523	Sodium-dependent multivitamin transmembrane transporter activity	2	3	0.0486	SLC23A2, LOC102159690
MF	GO:0015205	Nucleobase transmembrane transporter activity	2	3	0.0486	SLC23A2, LOC102159690
BP	GO:0015851	Nucleobase transport	2	3	0.0486	SLC23A2, LOC102159690
CC	GO:0070062	Extracellular exosome	20	2283	0.0486	TXN, TXNDC8, MGST3, CADM4, PI16, CTSH, ABCB1, FBP2, RPL15, ITIH3, PDHB, PEBP1, PPA1, GCA, HSPE1, SPHKAP, EFHD1, ENTPD6, AK2, GLA

Significantly enriched GO terms of upregulated genes in high PE compared to low PE placentas on day 95 of gestation in pigs. Level of significance P < 0.05. ^aMF Molecular function, BP Biological process, CC Cellular component, GO Gene ontology, DEG Differentially expressed genes, FDR P-value False discovery rate adjusted P-value, ^bSLC23A2 Solute carrier family 23 member 2, LOC102159690 solute carrier family 23 member 2-like, TXN Thioredoxin, TXNDC8 Thioredoxin domain-containing protein 8, MGST3 Microsomal glutathione S-transferase 3, CADM4 Cell adhesion molecule 4, PI16 Peptidase inhibitor 16 precursor, CTSH Pro-cathepsin H, ABCB1 ATP-binding cassette subfamily B member 1 isoform X2, FBP2 Fructose-1, 6-biphosphatase isoenzyme 2, RPL15 Ribosomal protein L15, ITIH3 Inter-alpha-trypsin inhibitor heavy chain H3, PDHB Pyruvate dehydrogenase E1 component subunit beta, PEBP1 Phosphatidylethanolamine-binding protein 1, PPA1 Inorganic pyrophosphatase, GCA Grancalcin, HSPE1 10 KDa heat shock protein, mitochondrial, SPHKAP A-kinase anchoring protein, EFHD1 EF-hand domain-containing protein D1 isoform X2, ENTPD6 Ectonucleoside triphosphate diphosphohydrolase 6, AK2 Adenylate kinase 2, GLA Alpha-galactosidase A

ISSN: 1471-2164