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Table 5 Number of top300 and random300 intervals containing eQTL, containing variants associated with local GEBV and showing a significant correlation between local GEBV and gene expression

From: Overlap between eQTL and QTL associated with production traits and fertility in dairy cattle

  

top300

random300

cell type

trait

nE

nC

nEG

nEC

nEGC

nE

nC

nEG

nEC

nEGC

milk

milk

27

10

3

2

1

16

9

6

1

1

fat

26

11

10

3

3

16

9

6

1

1

prot

23

6

5

1

0

16

9

6

1

1

fat%

25

11

9

1

1

16

8

5

1

0

prot%

29

14

11

2

2

16

9

5

1

1

fert

24

16

3

2

2

16

8

6

1

1

WBC

milk

58

20

27

13

11

36

15

20

6

5

fat

48

18

28

12

10

36

15

20

6

6

prot

45

24

23

10

9

36

14

20

6

5

fat%

56

25

25

12

7

36

14

18

5

4

prot%

61

25

39

10

10

36

14

19

6

5

fert

55

30

24

12

8

36

16

21

6

6

  1. Intervals were selected as the 300 non-overlapping intervals that explained most genetic variance (top300) or 300 randomly selected intervals (random300), the black dots show how many of the intervals containing at least one eQTL (nE) contain a variant that is associated with the eQTL and whose genotype correlates with the local GEBV of the interval (nEG), the blue dots show how many of the intervals with a significant correlation between local GEBV and gene expression (nC) contain an eQTL (nEC) that is correlated with the local GEBV of the interval, with consistent directions of effects (nEGC), WBC white blood cells, milk milk yield, fat fat yield, prot protein yield, fatPerc fat percentage, protPerc protein percentage, fert fertility