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Table 5 Number of top300 and random300 intervals containing eQTL, containing variants associated with local GEBV and showing a significant correlation between local GEBV and gene expression

From: Overlap between eQTL and QTL associated with production traits and fertility in dairy cattle

   top300 random300
cell type trait nE nC nEG nEC nEGC nE nC nEG nEC nEGC
milk milk 27 10 3 2 1 16 9 6 1 1
fat 26 11 10 3 3 16 9 6 1 1
prot 23 6 5 1 0 16 9 6 1 1
fat% 25 11 9 1 1 16 8 5 1 0
prot% 29 14 11 2 2 16 9 5 1 1
fert 24 16 3 2 2 16 8 6 1 1
WBC milk 58 20 27 13 11 36 15 20 6 5
fat 48 18 28 12 10 36 15 20 6 6
prot 45 24 23 10 9 36 14 20 6 5
fat% 56 25 25 12 7 36 14 18 5 4
prot% 61 25 39 10 10 36 14 19 6 5
fert 55 30 24 12 8 36 16 21 6 6
  1. Intervals were selected as the 300 non-overlapping intervals that explained most genetic variance (top300) or 300 randomly selected intervals (random300), the black dots show how many of the intervals containing at least one eQTL (nE) contain a variant that is associated with the eQTL and whose genotype correlates with the local GEBV of the interval (nEG), the blue dots show how many of the intervals with a significant correlation between local GEBV and gene expression (nC) contain an eQTL (nEC) that is correlated with the local GEBV of the interval, with consistent directions of effects (nEGC), WBC white blood cells, milk milk yield, fat fat yield, prot protein yield, fatPerc fat percentage, protPerc protein percentage, fert fertility