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Table 6 Intervals containing eQTL and QTL

From: Overlap between eQTL and QTL associated with production traits and fertility in dairy cattle

cell type

trait

chr

start (bp)

end (bp)

eQTL gene

topVar

annotation

p_eQTL

p_cor

milk

milk

29

42,610,883

42,860,883

ENSBTAG00000037645

42,829,338

5′ UTR MARK2

5.6 × 10−06

6.3 × 10− 06

milk

fat

18

1,601,923

1,851,923

FUK

1,840,070

intron AARS

5.1 × 10− 06

2.5 × 10−07

milk

prot%

18

1,550,757

1,800,757

FUK

1,666,278

intron COG4

3.8 × 10−11

8.1 × 10−15

WBC

milk

3

25,131,248

25,381,248

SPAG17

25,150,562

intron SPAG17

1.2 × 10−06

5.5 × 10−12

WBC

milk

5

104,173,293

104,423,293

NCAPD2

104,278,115

dns MRPL51

4.1 × 10−20

4.0 × 10−07

WBC

milk

18

18,190,766

18,440,766

BRD7

18,301,292

intron ZNF423

8.9 × 10−06

2.4 × 10−10

WBC

milk

23

31,068,838

31,318,838

BTN1A1

31,095,692

intergenic

6.3 × 10−08

1.5 × 10−06

WBC

milk

26

21,889,732

22,139,732

TWNK

21,901,063

ups LBX1

9.7 × 10−07

3.3 × 10−07

WBC

fat

14

2,753,849

3,003,849

FAM83H

2,755,467

synon LY6K

2.1 × 10−06

9.7 × 10−06

WBC

fat

18

1,601,923

1,851,923

FUK

1,612,928

ups IL34 & dns SF3B3

2.6 × 10−07

8.6 × 10−09

WBC

fat

18

18,190,766

18,440,766

BRD7

18,301,292

intron ZNF423

8.9 × 10−06

3.1 × 10−12

WBC

fat

23

9,700,270

9,950,270

C6orf222

9,728,266

ups CLPS

1.3 × 10−07

2.9 × 10−06

WBC

fat

26

21,139,834

21,389,834

TWNK

21,142,651

intron SCD

5.4 × 10−06

5.3 × 10− 06

WBC

fat

26

21,889,732

22,139,732

TWNK

21,893,176

dns LBX1

1.5 × 10−07

2.6 × 10−06

WBC

prot

11

104,113,835

104,363,835

ABO

104,225,654

intergenic

3.8 × 10−07

5.9 × 10−06

WBC

prot

18

18,190,766

18,440,766

BRD7

18,301,292

intron ZNF423

8.9 × 10−06

9.3 × 10−11

WBC

fat%

5

75,536,412

75,786,412

ENSBTAG00000012192

75,596,191

intergenic

9.6 × 10−07

4.5 × 10−06

WBC

fat%

5

104,120,905

104,370,905

NCAPD2

104,139,091

intron ZNF384

3.6 × 10−07

2.2 × 10−06

WBC

fat%

26

22,005,004

22,255,004

TWNK

22,005,517

intron BTRC

5.4 × 10−07

1.9 × 10− 07

WBC

prot%

5

24,074,711

24,324,711

CEP83

24,074,711

intron PLXNC1

3.2 × 10−06

1.8 × 10−12

WBC

prot%

11

104,168,845

104,418,845

ABO

104,225,654

intergenic

3.8 × 10−07

4.2 × 10−06

WBC

prot%

14

2,132,257

2,382,257

MAPK15

2,236,999

splice MAPK15

4.7 × 10−06

2.2 × 10− 06

WBC

prot%

18

1,550,757

1,800,757

FUK

1,673,395

intron COG4

1.1 × 10−39

7.0 × 10−38

WBC

prot%

18

2,187,925

2,437,925

FUK

2,200,039

intron FA2H

3.4 × 10−06

3.6 × 10−07

WBC

prot%

26

24,899,228

25,149,228

ENSBTAG00000038540

25,027,259

intron CFAP43

1.3 × 10−06

2.3 × 10−08

WBC

fert

6

38,538,611

38,788,611

FAM184B

38,585,743

intron LAP3

9.5 × 10−07

9.8 × 10−06

WBC

fert

10

37,985,065

38,235,065

CDAN1

38,017,802

intergenic

3.0 × 10−07

2.0 × 10−08

WBC

fert

21

48,591,579

48,841,579

SSTR1

48,641,167

intergenic

6.9 × 10−06

1.8 × 10−06

  1. Chr chromosome, topVar position in basepair (pb) of variant with strongest association with eQTL and localGEBV, annotation functional annotation of topVar, dns downstream, ups upstream, p_eQTL p-value eQTL analysis, p_cor p-value correlation local GEBV and gene expression, WBC white blood cells