Table 3 Top 15 down-regulated genes (L-lactate vs. NaCl vehicle control)
Gene Symbol | Description | FC | ANOVA | FDR |
|---|---|---|---|---|
VNN1 | vanin 1 | −2.82 | 1.31E-07 | 1.20E-05 |
SLC27A2 | solute carrier family 27 (fatty acid transporter), member 2 | − 2.68 | 2.00E-06 | 6.20E-05 |
GFRA1 | GDNF family receptor alpha 1 | −2.65 | 1.04E-08 | 3.00E-06 |
PRPS2 | phosphoribosyl pyrophosphate synthetase 2 | −2.64 | 5.52E-09 | 2.00E-06 |
PPM1K | protein phosphatase, Mg2+/Mn2+ dependent, 1 K | −2.55 | 1.08E-09 | 8.78E-07 |
SLC1A5 | solute carrier family 1 (neutral amino acid transporter), member 5 | −2.45 | 4.74E-07 | 2.70E-05 |
RANGRF | RAN guanine nucleotide release factor | −2.41 | 2.00E-06 | 7.30E-05 |
MYC | v-myc avian myelocytomatosis viral oncogene homolog | −2.40 | 8.02E-08 | 9.00E-06 |
ATF7IP2 | activating transcription factor 7 interacting protein 2 | −2.40 | 2.00E-06 | 6.90E-05 |
LOC508666 | C-C motif chemokine 23 | −2.36 | 2.19E-07 | 1.70E-05 |
IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | −2.34 | 2.90E-07 | 2.00E-05 |
GPT | glutamic-pyruvate transaminase (alanine aminotransferase) | −2.31 | 2.62E-07 | 1.90E-05 |
CYP19A1 | cytochrome P450, family 19, subfamily A, polypeptide 1 | −2.29 | 9.86E-08 | 1.00E-05 |
SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | −2.27 | 3.46E-07 | 2.20E-05 |
B3GALT2 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2 | −2.20 | 3.15E-07 | 2.10E-05 |