Table 4 Prediction of kinase fusion events at different dilution levels
From: Comprehensive kinome NGS targeted expression profiling by KING-REX
KARPAS 299 (ALK) | U-118 MG (ROS1) | Kinase | FC | P-value | IN_A | IN_B | OUT_A | OUT_B | Class |
|---|---|---|---|---|---|---|---|---|---|
100.0 | 0.0 | ALK | 15.8 | 2.00E-308 | 12.8 | 12.9 | 0.0 | 0.0 | TP |
87.5 | 12.5 | ALK | 6.5 | 0 | 13.0 | 12.8 | 6.4 | 6.3 | TP |
87.5 | 12.5 | ROS1 | 7.4 | 3.46E-078 | 7.7 | 7.6 | 1.6 | 0.0 | TP |
75.0 | 25.0 | ALK | 5.3 | 3.11E-124 | 12.6 | 12.8 | 7.5 | 7.2 | TP |
75.0 | 25.0 | ROS1 | 6.8 | 1.60E-075 | 8.7 | 8.7 | 0.0 | 3.0 | TP |
50.0 | 50.0 | ROS1 | 9.6 | 3.09E-194 | 9.8 | 9.8 | 0.0 | 1.6 | TP |
50.0 | 50.0 | ALK | 3.7 | 5.46E-105 | 12.2 | 12.1 | 8.5 | 8.3 | TP |
25.0 | 75.0 | ROS1 | 10.3 | 6.40E-167 | 10.6 | 10.3 | 0.0 | 1.6 | TP |
25.0 | 75.0 | ALK | 2.35 | 6.75E-028 | 11.25 | 11.36 | 8.68 | 9.13 | FN |
12.5 | 87.5 | ROS1 | 11.3 | 2.49E-152 | 10.7 | 10.7 | 1.0 | 0.0 | TP |
12.5 | 87.5 | ALK | 1.40 | 2.17E-015 | 10.95 | 10.77 | 9.31 | 9.34 | FN |
0.0 | 100.0 | ROS1 | 13.9 | 4.58E-174 | 10.9 | 10.7 | 0.0 | 0.0 | TP |