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Fig. 3 | BMC Genomics

Fig. 3

From: aFold – using polynomial uncertainty modelling for differential gene expression estimation from RNA sequencing data

Fig. 3

Illustration of the aFold approach with the HapMap-CEU data set. Seven genes on sex chromosomes are marked by red color. (a) and (c) Raw fold change (without shrinkage) under qtotal and geometric normalization, respectively. Five genes on sex chromosomes are out of y-axis range. (b) and (d) Fold change values calculated through the aFold (qtotal) and DESeq2 (geometric) approaches, respectively. All seven genes from sex chromosomes show largest fold changes in the aFold result. Four genes on sex chromosomes are out of y-axis range in the DESeq2 result

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