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Table 3 Composition of 24-gene classifiers distinguishing radiation exposure. Features were selected using the greedy pairs method using Il10−/− mouse data as the training set

From: Impact of inflammatory signaling on radiation biodosimetry: mouse model of inflammatory bowel disease

  UniqueID Symbol Name Parametric p-value Geom mean of intensities in Irradiated Geom mean of intensities in Controls Fold-change (Irradiated/Controls)
1 A_55_P2108943 Ccr6 chemokine (C-C motif) receptor 6 < 1e-07 11.77 554.18 0.021
2 A_51_P248122 Bbc3 BCL2 binding component 3 < 1e-07 1019.01 263.9 3.86
3 A_51_P378298 Fcmr Fc fragment of IgM receptor < 1e-07 41.34 1536.63 0.027
4 A_51_P304859 Zfand6 zinc finger, AN1-type domain 6 4e-07 115.94 422.84 0.27
5 A_51_P371750 Marco macrophage receptor with collagenous structure < 1e-07 5630.68 341.13 16.51
6 A_52_P612803 Ccng1 cyclin G1 < 1e-07 483.89 90.38 5.35
7 A_51_P363947 Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) < 1e-07 1154.64 47.87 24.12
8 A_55_P2121856 Ier5l immediate early response 5-like < 1e-07 172.96 53.17 3.25
9 A_55_P2137496 Cd79a CD79A antigen (immunoglobulin-associated alpha) < 1e-07 138.15 1777 0.078
10 A_51_P205779 Cd5l CD5 antigen-like 6e-07 8412.39 1257.39 6.69
11 A_51_P329928 Phlda3 pleckstrin homology like domain, family A, member 3 < 1e-07 2635.66 186.27 14.15
12 A_52_P77080 Gypa glycophorin A < 1e-07 93.67 1314.36 0.071
13 A_55_P2007964 Cx3cr1 chemokine (C-X3-C motif) receptor 1 < 1e-07 46.72 374.07 0.12
14 A_55_P2051254 Pvt1 plasmacytoma variant translocation 1 < 1e-07 118.94 27.32 4.35
15 A_51_P327751 Ifit1 interferon-induced protein with tetratricopeptide repeats 1 < 1e-07 545.07 82.18 6.63
16 A_51_P226429 Rhobtb2 Rho-related BTB domain containing 2 1.2e-06 51.68 128.33 0.4
17 A_51_P359570 Ifit3 interferon-induced protein with tetratricopeptide repeats 3 < 1e-07 2195.72 75.33 29.15
18 A_52_P497625 A630001G21Rik RIKEN cDNA A630001G21 gene 1.4e-06 40.17 113.97 0.35
19 A_66_P120987 Cd79a CD79A antigen (immunoglobulin-associated alpha) < 1e-07 21.65 180.7 0.12
20 A_55_P2105256 Trim47 tripartite motif-containing 47 < 1e-07 373.14 76.03 4.91
21 A_55_P1958275 Bcl11a B cell CLL/lymphoma 11A (zinc finger protein) < 1e-07 9.03 228.33 0.04
22 A_52_P180565 2310061I04Rik RIKEN cDNA 2310061I04 gene 3.3e-06 158.13 373.06 0.42
23 A_52_P390944 Chst3 carbohydrate (chondroitin 6/keratan) sulfotransferase 3 < 1e-07 8.68 274.93 0.032
24 A_55_P2097474 Creb5 cAMP responsive element binding protein 5 6.6e-06 1535.01 3450.09 0.44