Fig. 2

DNA methylation status of differentially expressed genes between the non-decidualized and decidualized ESCs. a and b: Median (50%), 25 and 75% tiles of beta-values of up-regulated 2419 genes (a) and down-regulated 2276 genes (b) are shown in the non-decidualized and decidualized ESCs. Vertical and horizontal lines show beta-values the position relative to the transcription start site (from − 1500 to + 4000 bp). c: Median (50%), 25 and 75% tiles of beta-values of the genes without expression in both types of ESC (9328 genes) are shown in the non-decidualized and decidualized ESCs. d: DNA methylation levels (mean ± SD, from − 300 to + 700) of the non-decidualized and decidualized ESCs of up-regulated genes, down-regulated genes, and genes without expression in both types of ESC are shown in boxplots. a, p < 0.01 vs. the non-decidualized ESCs of up-regulated genes; b, p < 0.01 vs. the decidualized ESCs of up-regulated genes; c, p < 0.01 vs. the non-decidualized ESCs of down-regulated genes; d, p < 0.01 vs. the decidualized ESCs of down-regulated genes