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Table 1 Comparison of the four tools on three datasets: S. aureus, human chromosome 14 and whole human genome for NA12878, whose draft genomes have 23, 3934, and 220,318 gaps respectively

From: GAPPadder: a sensitive approach for closing gaps on draft genomes with short sequence reads

Species

Gap Num.

Methods

Gaps fully closed

S. aureus

23

GAPPadder

9

  

GapCloser

2

  

GapFiller

1

  

Sealer

2

H. chrom 14

3934

GAPPadder

1670

  

GapCloser

1184

  

GapFiller

732

  

Sealer

559

NA12878

220,318

GAPPadder

130,371

  

GapCloser

Out of memory

  

GapFiller

Not finished (After 725 hrs)

  

Sealer

110,876

  1. Overall, GAPPadder closes more gaps than the other three tools on the these datasets