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Fig. 1 | BMC Genomics

Fig. 1

From: Overlapping and unique roles played by ROCK1 and 2 in the modulation of coding and long noncoding RNA expression

Fig. 1

Overview of the microarray data. a Heatmaps Heatmaps of DElncRNAs (a1) and (a3) and DEmRNAs (a2) and (a4) in R1 and R2 compared with Con and in a comparison between R1 and R2 (a5) and (a6) are shown. Red indicates higher expression, while green indicates lower expression. b Scatter plots Scatter plots of differentially expressed lncRNAs (b1) and (b3) and mRNAs (b2 and b4) in R1 and R2 compared with Con. DElncRNAs (b5) and DEmRNAs (b6) in R1 compared with those in R2. The X-axis of the scatter plot represents the normalized signal values from the control group, and the Y-axis of the scatter plot represents the normalized signal values from the test group. The plots falling on the Y = X line (the median line in the figure) represent no signal value differences between the two chips. The plots falling outside of the 45° line on both sides of the median line represent signal value differences between the two chips with a fold change > 2 or < 0.5. The scatter plots show the genes that were upregulated and downregulated by 2-fold with red and green plots, respectively. c Volcano plots Volcano plots of DElncRNAs (c1) and (c3) and DEmRNAs (c2) and (c4) in R1 and R2 compared to Con. DElncRNAs (c5) and DEmRNAs (c6) in R1 compared with R2. The volcano plots were constructed using the fold change values and p-values. The X axis represents Log2 (fold change), and the Y axis represents -log10 (p-value). The vertical lines correspond to a 2.0-fold increased and decreased change, and the horizontal line represents a p-value = 0.05. The red and green dots represent the upregulated and downregulated genes, respectively

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