Table 3 Gene ontology terms overrepresented among differentially expressed genes in liver and muscle
Term | Count | B-H p-value | |
|---|---|---|---|
GO terms overrepresented among DEGs with lower expression in the LRFI group vs HRFI group | |||
GO:0006612~protein targeting to membrane | 10 | 2.59E-02 | DMTN, GAS6, RPL18A, RPL3, RPS5, RPS11, RPS13, RPS18, RPS19, SSR2 |
GO:0030198~extracellular matrix organization | 12 | 5.45E-02 | CREB3L1, FMOD, GAS6, HTRA1, ITGA3, LTBP2, MMP15, MMP2, NOTCH1 OLFML2B, PDGFA TIMP |
GO terms overrepresented among DEGs with higher expression in the LRFI group vs HRFI group | |||
GO:0006952~defense response | 32 | 9.10E-04 | ADAR, CASP1, CUL1, CXCL10, DDX3X, DHX58, HERC5, IFI27, IFI44L, IFIT1,SGMS1, IFIT2, IFIT3, IFIT5 IFNGR1, IL1RAP, MX1, MX2, NLRP3, NR1D2,OASL, PARP9, PLGRKT, PSME4, RABGEf1, RORA, RSAD2, SP140, TRAF6, TRIM21, XAF1, ZBP1, |
GO:0009607~response to biotic stimulus | 23 | 1.21E-03 | ABCA1, ADAR, CASP1, CCDC47, CXCL10, DDX3X, DHX58, HERC5, IFI44L, IFIT1, IFIT2, IFIT3, IFIT5, IFNGR1, MX1, MX2, NLRP3, OASL, RSAD2, TRAF6, CMPK2, FMO1, SGMS1 |
GO:0044764~multi-organism cellular process | 24 | 1.42E-03 | ADAR, CXCL10, DDX3X, DHX58, HERC5, IFI44L, IFIT1, IFIT3, IFIT5, IFNGR1, MX1, MX2, NLRP3, NUP153, OASL, PROX1, RSAD2, TOP1, TRIM21, ZMYND11, CFLAR, CUL1, IFIT2, USP7 |
GO:0034097~response to cytokine | 20 | 6.75E-03 | ADAR, CXCL10, IFI27, IFIT1, IFIT2, IFIT3, IL1RAP, MX1, MX2, OASL, PARP9, PSME4, RABGEF1, RORA, SGMS1, TRAF6, TRIM21, XAF1, IFNGR1, RSAD2 |