ORF
|
protein ID
|
ChEMBL ID
|
Drug name
|
Mechanism of Action
|
---|
Rv0817c
|
NP_215332.1
|
CHEMBL2095222
|
ocriplasmin
|
Laminin hydrolytic enzyme inhibitor
|
Rv2927c
|
NP_217443.1
|
CHEMBL2105700
|
bedaquiline fumarate
|
ATP synthase inhibitor
|
Rv1303
|
NP_215819.1
|
CHEMBL3989689
|
squalamine
|
Sodium/hydrogen exchanger 3 inhibitor
|
Rv2908c
|
NP_217424.1
|
CHEMBL564085
|
troleandomycin
|
70S ribosome inhibitor
|
Rv2926c
|
NP_217442.1
|
CHEMBL614
|
pyrazinamide
|
Fatty acid synthase inhibitor
|
Rv0312
|
NP_214826.1
|
CHEMBL1201780
|
carglumic acid
|
Carbamoyl-phosphate synthase inhibitor
|
- Six essential HPs were identified with potential drug targets