Fig. 1

Changes of RNA levels as monitored by microarrays throughout the growth phases. Levels of RNAs in later growth phases were normalized to RNA levels in exponential phase. Box plots (a) give an overview on the transcriptome variability of the different samples. Kernel density estimators (KDE) (b) compare the distribution of growth phase-dependent changes in gene expression. The heat map (c) gives a global overview of the changes in RNA levels at single gene resolution. The ranking of genes is based upon the degree of log₂FC observed in transition phase, with the highest increases in transcript abundance in the transition phase appearing at the top of the heat map. Indicated underneath the heat map is the total number of transcripts detected at each growth phase