Fig. 7

Interspecies comparison of gene repertoire and expression among adult O. felineus, O. viverrini, and C. sinensis. a. Proportional Venn-diagram of orthologous clusters identified in three species by ProteinOrtho. Non-orthologous genes that match to Swiss-Prot/Pfam datasets or genomes of other two flukes are shown as hatched areas. b. Differences in gene expression of adult worms. The genes with expression values differing more than fourfold (p < 0.01) are colored dark red (OF, O. felineus; OV, O. viverrini; CS, C. sinensis). The Pearson correlation coefficient for the pair O. viverrini–O. felineus was r = 0.89 (p-value = 0); for the pair O. felineus–C. sinensis was r = 0.88 (p-value = 0)