Table 2 Genes with ≥2 heterozygous alleles (HAs) across all sputum samples, ordered by greatest number of HAs per base
Gene | Heterozygous alleles per base | Total number of heterozygous alleles | Functional category | ||
|---|---|---|---|---|---|
Sputum | MGIT | Sputum | MGIT | ||
rv1319c | 0.021 | 0.021 | 33 | 33 | Metabolism and respiration |
rrs | 0.016 | 0.000 | 25 | 0 | 16S ribosomal RNA |
rrl | 0.006 | 0.000 | 19 | 0 | 23S ribosomal RNA |
ppsA | 0.003 | 0.001 | 15 | 4 | Lipid metabolism |
rv2082 | 0.006 | 0.006 | 13 | 14 | Unknown function |
accE5 | 0.006 | 0.000 | 3 | 0 | Lipid metabolism |
lppB | 0.005 | 0.005 | 3 | 3 | Probable surface lipoprotein |
pks12 | 0.000 | 0.001 | 3 | 10 | Lipid metabolism |
rv2319c | 0.003 | 0.005 | 3 | 4 | Stress protein |
lppA | 0.003 | 0.002 | 2 | 1 | Probable surface lipoprotein |
rpoC | 0.001 | 0.001 | 2 | 3 | RNA polymerase beta’ subunit |
rv3888c | 0.002 | 0.001 | 2 | 1 | Probable membrane protein |
vapC25 | 0.005 | 0.000 | 2 | 0 | Possible toxin |
vapC31 | 0.005 | 0.002 | 2 | 1 | Possible toxin |