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Table 4 Significant SNPs assigned to candidate genes for oligosaccharide synthesis in Danish Jersey

From: A genome-wide association study reveals specific transferases as candidate loci for bovine milk oligosaccharides synthesis

Gene

Gene name

Chr.b

#SNPc

Highest

-log10(P-value)

PVE%d

Traita

ABO

ABO blood group (transferase A. alpha 1–3-N-acetylgalactosaminyltransferase; transferase B. alpha 1–3-galactosyltransferase)

11

19

52.879

55.87

2_1_0_0_0 isomer 1

GALNT17

polypeptide N-acetylgalactosaminyltransferase 17 like

25

28

27.690

33.99

3_6_1_0_0

GALNT17

polypeptide N-acetylgalactosaminyltransferase 17 like

25

26

23.712

29.74

5_4_1_0_0

GALNT17

polypeptide N-acetylgalactosaminyltransferase 17 like

25

18

20.326

25.92

4_5_1_0_0

GALNT17

polypeptide N-acetylgalactosaminyltransferase 17 like

25

12

14.215

18.55

4_4_1_0_0

GALNT17

polypeptide N-acetylgalactosaminyltransferase 17 like

25

15

13.206

17.28

5_4_0_0_0

MAN1C1

mannosidase alpha class 1C member 1

2

6

6.677

8.64

3_1_0_0_0 LNT

MAN1C1

mannosidase alpha class 1C member 1

2

6

5.654

7.23

4_2_0_0_0 LNH

ST6GALNAC6

ST6 N-acetylgalactosaminide alpha-2.6-sialyltransferase 6

11

1

6.599

8.53

2_1_0_0_0 isomer 1

GLT6D1

glycosyltransferase 6 domain containing 1

11

2

5.556

7.10

2_1_0_0_0 isomer 1

PIGV

phosphatidylinositol glycan anchor biosynthesis class V

2

2

5.534

7.07

4_2_0_0_0 LNH

PIGV

phosphatidylinositol glycan anchor biosynthesis class V

2

1

5.328

6.78

3_1_0_0_0 LNT

LFNG

LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

25

1

4.763

6.00

5_4_1_0_0

LFNG

LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

25

1

4.523

5.67

4_4_1_0_0

GALNT14

polypeptide N-acetylgalactosaminyltransferase 14

11

3

3.979

4.91

3_1_0_0_0 LNT

COLGALT2

collagen beta(1-O)galactosyltransferase 2

16

2

3.906

4.81

4_1_0_0_0

SIGLEC1

sialic acid binding Ig like lectin 1

13

1

3.850

4.73

3_6_1_0_0

  1. aOligosaccharides are represented by their monosaccharide compositions, denoted as Hex_HexNAc_Fuc_NeuAc_NeuGc
  2. bChr chromosome
  3. c#SNP number of significant SNPs assigned to candidate gene
  4. dPVE% Percentage of phenotypic variation explained