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Table 4 Significant SNPs assigned to candidate genes for oligosaccharide synthesis in Danish Jersey

From: A genome-wide association study reveals specific transferases as candidate loci for bovine milk oligosaccharides synthesis

Gene Gene name Chr.b #SNPc Highest -log10(P-value) PVE%d Traita
ABO ABO blood group (transferase A. alpha 1–3-N-acetylgalactosaminyltransferase; transferase B. alpha 1–3-galactosyltransferase) 11 19 52.879 55.87 2_1_0_0_0 isomer 1
GALNT17 polypeptide N-acetylgalactosaminyltransferase 17 like 25 28 27.690 33.99 3_6_1_0_0
GALNT17 polypeptide N-acetylgalactosaminyltransferase 17 like 25 26 23.712 29.74 5_4_1_0_0
GALNT17 polypeptide N-acetylgalactosaminyltransferase 17 like 25 18 20.326 25.92 4_5_1_0_0
GALNT17 polypeptide N-acetylgalactosaminyltransferase 17 like 25 12 14.215 18.55 4_4_1_0_0
GALNT17 polypeptide N-acetylgalactosaminyltransferase 17 like 25 15 13.206 17.28 5_4_0_0_0
MAN1C1 mannosidase alpha class 1C member 1 2 6 6.677 8.64 3_1_0_0_0 LNT
MAN1C1 mannosidase alpha class 1C member 1 2 6 5.654 7.23 4_2_0_0_0 LNH
ST6GALNAC6 ST6 N-acetylgalactosaminide alpha-2.6-sialyltransferase 6 11 1 6.599 8.53 2_1_0_0_0 isomer 1
GLT6D1 glycosyltransferase 6 domain containing 1 11 2 5.556 7.10 2_1_0_0_0 isomer 1
PIGV phosphatidylinositol glycan anchor biosynthesis class V 2 2 5.534 7.07 4_2_0_0_0 LNH
PIGV phosphatidylinositol glycan anchor biosynthesis class V 2 1 5.328 6.78 3_1_0_0_0 LNT
LFNG LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 25 1 4.763 6.00 5_4_1_0_0
LFNG LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 25 1 4.523 5.67 4_4_1_0_0
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14 11 3 3.979 4.91 3_1_0_0_0 LNT
COLGALT2 collagen beta(1-O)galactosyltransferase 2 16 2 3.906 4.81 4_1_0_0_0
SIGLEC1 sialic acid binding Ig like lectin 1 13 1 3.850 4.73 3_6_1_0_0
  1. aOligosaccharides are represented by their monosaccharide compositions, denoted as Hex_HexNAc_Fuc_NeuAc_NeuGc
  2. bChr chromosome
  3. c#SNP number of significant SNPs assigned to candidate gene
  4. dPVE% Percentage of phenotypic variation explained