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Table 1 Enrichment analysis of the human dataset for the top 15 most connected clusters

From: A hypergraph-based method for large-scale dynamic correlation study at the transcriptomic scale

Group label Group size Hyperedges involved GOBPID Term P-value
67 109 210 GO:0030968 endoplasmic reticulum unfolded protein response 3.39E-05
    GO:0008015 blood circulation 3.81E-03
73 104 170 GO:0008202 steroid metabolic process 6.38E-04
    GO:0009063 cellular amino acid catabolic process 2.38E-03
60 114 142 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway 2.55E-05
    GO:0015698 inorganic anion transport 3.83E-04
70 104 120 GO:0072330 monocarboxylic acid biosynthetic process 3.21E-03
    GO:0019730 antimicrobial humoral response 6.04E-03
55 123 96 GO:0031349 positive regulation of defense response 3.26E-03
    GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process 7.11E-03
15 266 83 GO:0006022 aminoglycan metabolic process 1.70E-03
    GO:0090066 regulation of anatomical structure size 2.31E-03
69 105 81 GO:0006302 double-strand break repair 1.47E-03
    GO:0001701 in utero embryonic development 2.93E-03
72 104 77 GO:0098742 cell-cell adhesion via plasma-membrane adhesion molecules 5.97E-03
    GO:0031365 N-terminal protein amino acid modification 7.54E-03
68 108 76 GO:0048608 reproductive structure development 2.43E-03
    GO:0008015 blood circulation 3.81E-03
77 100 71 GO:0051493 regulation of cytoskeleton organization 1.02E-03
    GO:0060560 developmental growth involved in morphogenesis 3.71E-03
48 138 68 GO:0051640 organelle localization 2.60E-04
    GO:0006767 water-soluble vitamin metabolic process 2.21E-03
54 129 56 GO:0051017 actin filament bundle assembly 1.26E-03
    GO:0009100 glycoprotein metabolic process 3.50E-03
4 385 51 GO:0016569 covalent chromatin modification 3.52E-03
    GO:0072331 signal transduction by p53 class mediator 4.46E-03
22 233 51 GO:1901655 cellular response to ketone 2.65E-03
    GO:0010035 response to inorganic substance 8.21E-03
50 136 49 GO:0006414 translational elongation 1.45E-03
    GO:0002791 regulation of peptide secretion 4.27E-03
  1. For each cluster, the enriched term that include the most number of genes in the cluster is shown