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Table 1 Protease- and lipase-encoding genes modulated during the growth of Trichophyton rubrum on keratin and elastin

From: Trans-chalcone activity against Trichophyton rubrum relies on an interplay between signaling pathways related to cell wall integrity and fatty acid metabolism

ID

Gene product name

Keratin

Elastin

TERG_05923

Metallopeptidase

−6.10

–

TERG_03293

Hypothetical protein

−6.32

–

TERG_04809

Metalloproteinase 2

− 8.12

–

TERG_05652

Leucine aminopeptidase 1

+ 20.71

+ 8.05

TERG_04324

Metalloproteinase 4

+ 24.01

–

TERG_12606

Secreted dipeptidyl peptidase

+ 5.03

–

TERG_03400

Subtilisin-like protease 1

+ 5.17

–

TERG_03104

Signal peptidase i

+ 5.49

–

TERG_06552

Aspartic-type endopeptidase

+ 5.82

–

TERG_04769

Serine carboxypeptidase

+ 5.82

–

TERG_03248

Metalloproteinase 3

+ 6.72

–

TERG_02214

Carboxypeptidase 2

+ 6.79

–

TERG_08557

Carboxypeptidase s1

+ 7.24

–

TERG_08405

Leucine aminopeptidase 2

+ 8.31

–

TERG_05735

Dipeptidyl peptidase 4

+ 8.54

–

TERG_08201

Subtilisin-like protease 5

+ 9.06

–

TERG_03815

Subtilisin-like protease 3

+ 9.88

–

TERG_01617

Subtilisin-like protease 4

+ 9.98

–

TERG_01957

Alkaline serine protease

–

+ 6.52

TERG_03459

GDSL lipase acylhydrolase

–

+ 5.32

TERG_05317

Lipase 1

+ 11.54

–

TERG_04914

Spo7-like protein

+ 5.40

–

TERG_00899

Neutral ceramidase

+ 5.66

–

TERG_00127

Secretory phospholipase a2

+ 52.72

+ 7.01

TERG_03747

Phospholipase a2

+ 6.79

–

  1. +: induction; −: repression