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Table 3 The immune responses related DEGs and partial validation of RNA sequencing data by qRT-PCR

From: Transcriptome analysis reveals differential immune related genes expression in bovine viral diarrhea virus-2 infected goat peripheral blood mononuclear cells (PBMCs)

Gene ID Gene name Function annotation FC log2(B2/N)
RNA-Seq qRT-PCR
Down-regulated
 NC_030809.1_gene90 C1QA complement C1q subcomponent subunit A −3.03  
 NC_030809.1_gene93 C1QB complement C1q subcomponent subunit B −2.29  
 NC_030809.1_gene91 C1QC complement C1q subcomponent subunit C −1.42  
 NC_030814.1_gene546 CFD complement factor D −2.35  
 NC_030812.1_gene428 S-LE lysozyme −3.03  
 NC_030836.1_gene709 IFITM3 interferon-induced transmembrane protein 3 −1.36  
 NC_030834.1_gene266 LOC102188015 beta-defensin 103A −1.05 −0.5
 NC_030810.1_gene1245 S100A4 protein S100-A4 −1.76  
 NC_030808.1_gene1009 S100B protein S100-B −1.23  
 NC_030818.1_gene1111 FCN1 ficolin-1 −1.56  
 NC_030818.1_gene586 ANXA4 annexin A4 −1.54 −0.7
 NC_030813.1_gene593 ANXA3 annexin A3 −1.49 −0.9
 NC_030817.1_gene452 ANXA2 annexin A2 −1.29 −1.9
 NC_030826.1_gene194 CCL2 C-C motif chemokine 2 −1.61 −2.2
Up-regulated
 NC_030828.1_gene424 NFKBIA NF-kappa-B inhibitor alpha 1.27 1.3
 NC_030836.1_gene157 LOC102168428 serum amyloid A protein 1.31 2.2
 NC_030836.1_gene161 LOC100860781 serum amyloid A3 1.62  
 NC_030826.1_gene156 CCL3 C-C motif chemokine 3 1.48 1.5
 NC_030825.1_gene308 CCL22 C-C motif chemokine 22 1.48  
 NC_030826.1_gene155 CCL4 C-C motif chemokine 4 1.95 1.8
 NC_030826.1_gene163 CCL5 C-C motif chemokine 5 1.80 1.6
 NC_030809.1_gene360 CCL20 C-C motif chemokine 20 3.12 2.7
 NC_030813.1_gene567 CXCL10 C-X-C motif chemokine 10 1.16 1.2
 NC_030814.1_gene1059 ICAM1 intercellular adhesion molecule 1 1.54  
 NC_030830.1_gene594 TNF tumor necrosis factor alpha 1.62 3
 NC_030823.1_gene84 IL-10 interleukin-10 2.16 2.5
 NC_030830.1_gene686 IL-17A interleukin-17A 2.18 1.6
 NC_030811.1_gene808 IL-6 interleukin-6 2.28 2.4
 NC_030814.1_gene174 IL-12B interleukin-12 subunit beta 2.80 2.2
 NC_030814.1_gene828 GM-CSF granulocyte-macrophage colony-stimulating factor 3.30 2.45