From: hg19KIndel: ethnicity normalized human reference genome
Sanity Check while building compatible snpEff database | Genome | Compatible annotation database | Reference mRNA | Match percentage between the respective genome and refSeq | |
---|---|---|---|---|---|
Protein level | mRNA level | ||||
Existing baseline | hg19 | refGene | refSeq | 92.81 | 95.2 |
After replacing only minor SNP alleles with major alleles in hg19 | hg19K | refGene | refSeq | 85.79 | 70.48 |
After to replacing minor INDELS with major alleles in hg19K | hg19KIndel | refGeneKINDEL | refSeq | 85.75 | 69.96 |