Fig. 2
From: Recurrent miscalling of missense variation from short-read genome sequence data
a Recurrent false positive variants arise in a sequence-specific manner in three mouse strains. Similarities between these variant sets closely mirror the sequence similarity and relatedness between individual genomes. b Likewise, with human sequences, while a small set of recurrent false positive variants are common between all four individuals, the majority are highly ethnically-dependent to individual-specific. c Further to this, simulation of recurrent false positive variants from a closely related group of Omani individuals indicates that most are individual-specific, with a smaller number being population-specific. d Effect of read length on identification of Recurrent False Positives. Simulation of recurrent false positive variants with different length short-reads from the same genome (NA12878) demonstrates that most of these false positives are specific to read length