Skip to main content
Fig. 5 | BMC Genomics

Fig. 5

From: Assessing cell-specific effects of genetic variations using tRNA microarrays

Fig. 5

Predicted translation profiles for ADAMTS13 (a) and blood coagulation factor IX (F9) (b) transcripts computed with RiboTempo using the tRNA concentration of HeLa cells. The gray area marks the 10th–90th percentile. The position of exemplified sSNVs is marked with () and designated using the scheme: wild-type nucleotide, position, mutated nucleotide. c-e tRNA concentration within the tRNAThr (c), tRNAGly (d) and tRNAVal (e) families compared to those present in HeLa cells, which are set to 1. The synonymous SNP-induced codon is designated in red. For iPSCs, only the zero time point was reported in all panels. tRNA isoacceptors are depicted with their cognate codon and corresponding amino acid

Back to article page