Table 1 Ion channel genes in the zebra finch genome
From: Exploring the molecular basis of neuronal excitability in a vocal learner
HGNC Symbol | Alternate name | Full name | Zebra finch locus |
|---|---|---|---|
A. Sodium channels | |||
α subunits | |||
SCN1A | Nav1.1 | sodium voltage-gated channel alpha subunit 1 | ENSTGUG00000007356^ |
SCN2A | Nav1.2 | sodium voltage-gated channel alpha subunit 2 | ENSTGUG00000007152^* |
SCN3A | Nav1.3 | sodium voltage-gated channel alpha subunit 3 | ENSTGUG00000007034 |
SCN4A | Nav1.4 | sodium voltage-gated channel alpha subunit 4 | ENSTGUG00000003230 |
SCN5A | Nav1.5 | sodium voltage-gated channel alpha subunit 5 | ENSTGUG00000000531^ |
ENSTGUG00000000533^ | |||
SCN8A | Nav1.6 | sodium voltage-gated channel alpha subunit 8 | ENSTGUG00000003307 |
SCN9A | Nav1.7 | sodium voltage-gated channel alpha subunit 9 | ENSTGUG00000007470^* |
SCN10A | Nav1.8 | sodium voltage-gated channel alpha subunit 10 | ENSTGUG00000000476^* |
SCN11A | Nav1.9 | sodium voltage-gated channel alpha subunit 11 | chr2:5686797–5,719,627 |
β subunits | |||
SCN1B$ | sodium voltage-gated channel beta subunit 1 | MUGN01000920.1818309–818,447 | |
SCN2B | sodium voltage-gated channel beta subunit 2 | ENSTGUG00000017358 | |
MUGN01000074.12766152–2,766,960 | |||
SCN3B | sodium voltage-gated channel beta subunit 3 | ENSTGUG00000000607^ | |
SCN4B | sodium voltage-gated channel beta subunit 4 | ENSTGUG00000000230 | |
MUGN01000074.12777132–2,778,696 | |||
Acid-sensing | |||
ASIC1 | ACCN2 | acid sensing ion channel subunit 1 | ENSTGUG00000003637 |
ASIC2# | ACCN1 | acid sensing ion channel subunit 2 | ENSTGUG00000003212^* |
ENSTGUG00000003215^* | |||
ASIC3◆ | ACCN3 | acid sensing ion channel subunit 3 | ENSTGUG00000016020^* |
MUGN01000217.1876923–883,599 | |||
ASIC4 | ACCN4 | acid sensing ion channel subunit 4 | ENSTGUG00000006157* |
ASIC5◆ | ACCN5 | acid sensing ion channel subunit 5 | ENSTGUG00000005392 |
Leak channel | |||
NALCN | sodium leak channel, non selective | ENSTGUG00000010876 | |
Epithelial | |||
SCNN1A◆$ | SCNN1 | sodium channel epithelial 1 alpha subunit | ENSTGUG00000013342* |
SCNN1B | sodium channel epithelial 1 beta subunit | ENSTGUG00000005936 | |
SCNN1D◆ | sodium channel epithelial 1 delta subunit | ENSTGUG00000004091 | |
SCNN1G | sodium channel epithelial 1 gamma subunit | chr14:8747853–8,755,433 | |
B. Calcium channels | |||
L-type α subunits | |||
CACNA1S | Cav1.1 | calcium voltage-gated channel subunit alpha1 S | ENSTGUG00000001142* |
CACNA1C | Cav1.2 | calcium voltage-gated channel subunit alpha1 C | ENSTGUG00000012529^ |
ENSTGUG00000012538^ | |||
CACNA1D | Cav1.3 | calcium voltage-gated channel subunit alpha1 D | ENSTGUG00000006839* |
CACNA1F | Cav1.4 | calcium voltage-gated channel subunit alpha1 F | MUGN01000244.140490–59,194 |
N/P/Q/R- type α subunits | |||
CACNA1A | Cav2.1 | calcium voltage-gated channel subunit alpha1 A | MUGN01001147.1274884–306,034 |
CACNA1B | Cav2.2 | calcium voltage-gated channel subunit alpha1 B | ENSTGUG00000002855* |
CACNA1E | Cav2.3 | calcium voltage-gated channel subunit alpha1 E | ENSTGUG00000017352 |
T-type α subunits | |||
CACNA1G | Cav3.1 | calcium voltage-gated channel subunit alpha1 G | ENSTGUG00000009049* |
CACNA1H | Cav3.2 | calcium voltage-gated channel subunit alpha1 H | ENSTGUG00000006881* |
CACNA1I | Cav3.3 | calcium voltage-gated channel subunit alpha1 I | ENSTGUG00000010198* |
α2/δ subunits | |||
CACNA2D1 | calcium voltage-gated channel auxiliary subunit alpha2delta 1 | ENSTGUG00000002536^* | |
ENSTGUG00000002533^* | |||
CACNA2D2 | calcium voltage-gated channel auxiliary subunit alpha2delta 2 | ENSTGUG00000004703^* | |
ENSTGUG00000004711^* | |||
ENSTGUG00000004714^* | |||
CACNA2D3 | calcium voltage-gated channel auxiliary subunit alpha2delta 3 | ENSTGUG00000006966^* | |
CACNA2D4 | calcium voltage-gated channel auxiliary subunit alpha2delta 4 | ENSTGUG00000012579^ | |
β subunits | |||
CACNB1 | calcium voltage-gated channel auxiliary subunit beta 1 | MUGN01000261.12481145–2,492,038 | |
CACNB2 | calcium voltage-gated channel auxiliary subunit beta 2 | ENSTGUG00000001247* | |
CACNB3 | calcium voltage-gated channel auxiliary subunit beta 3 | ENSTGUG00000015546 | |
MUGN01000394.1996686–999,415 | |||
CACNB4 | calcium voltage-gated channel auxiliary subunit beta 4 | ENSTGUG00000012082^* | |
γ subunits | |||
CACNG1 | calcium voltage-gated channel auxiliary subunit gamma 1 | ENSTGUG00000004397^ | |
CACNG2 | stargazer, | calcium voltage-gated channel auxiliary subunit gamma 2 | ENSTGUG00000010725 |
stargazin | |||
CACNG3 | calcium voltage-gated channel auxiliary subunit gamma 3 | ENSTGUG00000006208* | |
CACNG4 | calcium voltage-gated channel auxiliary subunit gamma 4 | ENSTGUG00000004385* | |
CACNG5 | calcium voltage-gated channel auxiliary subunit gamma 5 | ENSTGUG00000004375* | |
CACNG7$ | calcium voltage-gated channel auxiliary subunit gamma 7 | MUGN01000421.1339861–356,707 | |
CACNG8$ | calcium voltage-gated channel auxiliary subunit gamma 8 | MUGN01000421.1325281–333,090 | |
Intracellular | |||
ITPR1 | IP3R1 | inositol 1,4,5-trisphosphate receptor type 1 | ENSTGUG00000010241^ |
ITPR2 | IP3R2 | inositol 1,4,5-trisphosphate receptor type 2 | ENSTGUG00000012196^ |
ITPR3 | IP3R3 | inositol 1,4,5-trisphosphate receptor type 3 | ENSTGUG00000001798 |
RYR1 | ryanodine receptor 1 | ENSTGUG00000016333^ | |
MUGN01000615.12737–83,931 | |||
RYR2 | ryanodine receptor 2 | ENSTGUG00000010491 | |
RYR3 | ryanodine receptor 3 | ENSTGUG00000011653^ | |
TPCN1 | TPC1 | two pore segment channel 1 | ENSTGUG00000009086 |
TPCN2◆ | TPC2 | two pore segment channel 2 | ENSTGUG00000005328 |
TPCN3◆✣ | TPC3 | two pore segment channel 3 | ENSTGUG00000007338^* |
ENSTGUG00000015038^* | |||
Sperm associated | |||
CATSPERB▽◆ | C14orf161 | cation channel sperm associated auxiliary subunit beta | MUGN01001095.110976025–10,976,136 |
CATSPERD▽◆$ | TMEM146 | cation channel sperm associated auxiliary subunit delta | MUGN01000898.110200480–10,200,746 |
CATSPERE▽◆ | C1orf101 | catsper channel auxiliary subunit epsilon | ENSTGUG00000008288^* |
MUGN01000667.120007852–20,020,082 | |||
CATSPER3▽◆ | cation channel sperm associated 3 | chr13_random:2493868–2,500,983 | |
MUGN01000154.1512621–517,332 | |||
C. Chloride channels | |||
CLCNs | |||
CLCN1 | CLC1 | chloride voltage-gated channel 1 | ENSTGUG00000013222* |
CLCN2 | CLC2 | chloride voltage-gated channel 2 | ENSTGUG00000010323* |
CLCN3 | CLC3 | chloride voltage-gated channel 3 | ENSTGUG00000006161 |
CLCN4 | CLC4 | chloride voltage-gated channel 4 | ENSTGUG00000008365 |
CLCN5$ | CLC5 | chloride voltage-gated channel 5 | ENSTGUG00000005324 |
CLCN6 | CLC6 | chloride voltage-gated channel 6 | ENSTGUG00000002366* |
CLCN7 | CLC7 | chloride voltage-gated channel 7 | ENSTGUG00000004211* |
CLCNK✝ | CLCK1 | chloride voltage-gated channel K✝ | ENSTGUG00000002023^* |
BSND | BART, DFNB73 | barttin CLCNK type accessory beta subunit A | chr8:22970234:22970413 |
CLICs | |||
CLIC2# | CLIC2b | chloride intracellular channel 2 | ENSTGUG00000004925 |
CLIC3$ | chloride intracellular channel 3 | ENSTGUG00000002341* | |
CLIC4 | CLIC4L | chloride intracellular channel 4 | ENSTGUG00000001132^* |
CLIC5 | chloride intracellular channel 5 | ENSTGUG00000013246 | |
CLIC6◆ | CLIC1L | chloride intracellular channel 6 | ENSTGUG00000004696 |
MUGN01000638.1213150–238,240 | |||
CLCC1◆ | MCLC | chloride channel CLIC like 1 | ENSTGUG00000004508* |
Calcium-activated | |||
ANO1 | TMEM16A | anoctamin 1 | ENSTGUG00000005385* |
ANO2 | TMEM16B | anoctamin 2 | ENSTGUG00000011938 |
ANO3 | TMEM16C | anoctamin 3 | ENSTGUG00000004669 |
ANO4 | TMEM16D | anoctamin 4 | ENSTGUG00000009008 |
ANO5 | TMEM16E | anoctamin 5 | ENSTGUG00000004532* |
ANO6 | TMEM16F | anoctamin 6 | ENSTGUG00000006024* |
ANO7▽ | TMEM16G | anoctamin 8 | MUGN01000068.1571318–573,272 |
ANO8 | TMEM16H | anoctamin 8 | ENSTGUG00000015909^* |
ANO9 | TMEM16J | anoctamin 9 | ENSTGUG00000006753 |
ANO10 | TMEM16K | anoctamin 10 | ENSTGUG00000003830 |
BEST1◆ | VMD2 | bestrophin 1 | ENSTGUG00000005934^* |
BEST3 | VMD2L3 | bestrophin 3 | ENSTGUG00000006968^ |
Volume regulated | |||
LRRC8A | LRRC8 | leucine rich repeat containing 8 VRAC subunit A | ENSTGUG00000004233 |
LRRC8B | leucine rich repeat containing 8 VRAC subunit B | ENSTGUG00000006230* | |
LRRC8C | leucine rich repeat containing 8 VRAC subunit C | ENSTGUG00000006226 | |
LRRC8D | LRRC5 | leucine rich repeat containing 8 VRAC subunit D | ENSTGUG00000006223 |
Other | |||
CFTR | cystic fibrosis transmembrane conductance regulator | ENSTGUG00000004828 | |
CLNS1A◆ | chloride nucleotide-sensitive channel 1A | ENSTGUG00000013030^ | |