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Table 2 Distribution of differentially methylated CpGs among the ovarian methylomes

From: Dynamic DNA methylation of ovaries during pubertal transition in gilts

  Detected CpGs DMCs between Pre- and In-puberty DMCs between Pre- and Post-puberty DMCs between In- and Post-puberty
Number Enrichment Number Enrichment Number Enrichment
Total 840,469 12,313 20,960 17,694
CGI 501,376 3813 0.30 (P < 2.22 × 10−16) 6324 0.29 (P < 2.22 × 10− 16) 5226 0.28 (P < 2.22 × 10− 16)
CGI shores 138,931 3161 1.74 (P < 2.22 × 10− 16) 5578 1.83 (P < 2.22 × 10− 16) 4778 1.87 (P < 2.22 × 10− 16)
CGI shelves 40,091 1141 2.04 (P < 2.22 × 10− 16) 2060 2.18 (P < 2.22 × 10− 16) 1672 2.08 (P < 2.22 × 10− 16)
Upstream 182,275 959 0.30 (P < 2.22 × 10− 16) 1678 0.31 (P < 2.22 × 10− 16) 1373 0.30 (P < 2.22 × 10− 16)
intron 219,465 4718 1.76 (P < 2.22 × 10− 16) 8051 1.76 (P < 2.22 × 10− 16) 6871 1.79 (P < 2.22 × 10− 16)
exon 214,079 1850 0.52 (P < 2.22 × 10− 16) 3376 0.56 (P < 2.22 × 10− 16) 2817 0.55 (P < 2.22 × 10− 16)
Downstream 46,202 759 1.12 (P < 2.22 × 10− 16) 1318 1.15 (P < 2.22 × 10− 16) 1138 1.18 (P < 2.22 × 10− 16)
Intergenic 178,448 4027 1.80 (P < 2.22 × 10− 16) 6537 1.68 (P < 2.22 × 10− 16) 5495 1.67 (P < 2.22 × 10− 16)
  1. Enrichment of DMCs for certain genomic regions was using a two-tailed Fisher’s exact test