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Table 6 The top ten canonical pathways for Holstein-Friesian steers offered the high-concentrate one diet

From: The effect of breed and diet type on the global transcriptome of hepatic tissue in beef cattle divergent for feed efficiency

HF.H1 Glutathione-mediated Detoxification ANPEP, GSTA4 , GSTM1 4.92E-08
2-amino-3-carboxymuconate Semialdehyde Degradation to Glutaryl-CoA ACMSD 1.693E-05
Branched-chain α-keto acid Dehydrogenase Complex DLD 0.00016
2-ketoglutarate Dehydrogenase Complex DLD 0.00024
2-oxobutanoate Degradation I DLD 0.00024
Glycine Cleavage Complex DLD 0.00034
Acetyl-CoA Biosynthesis I (Pyruvate Dehydrogenase Complex) DLD 0.00045
Fc Epsilon RI Signalling FCER1A, RAC1 0.00052
Phagosome Formation FCER1A, RAC1 0.00069
Aryl Hydrocarbon Receptor Signaling GSTM1, GSTA4 0.00076
  1. H1 high concentrate, phase 1, HF Holstein-Friesian; P-value = Fisher’s exact test P-value, bold text indicates gene downregulation in low-RFI steers