Table 1 Reconstructed EBP regulons of Clostridiales
From: Genomic reconstruction of σ54 regulons in Clostridiales
EBP | Target operon | Function | Distribution |
|---|---|---|---|
AcoR | acoABCL | Acetoin catabolism | Clostridium |
AdhR | adhA | Alcohol synthesis | Clostridium |
AguQ | aguDA, aguBC, aguQT | Agmatine metabolism | Clostridium |
AhcR | atoE-hbd-cotX | Butyrate/Butanol synthesis | Clostridium |
AorR | aor-moaD | Alcohol synthesis | Clostridium, Geosporobacter |
AtlR | atlEFG, atlD-tkt-rpi-araD-manB | Pentitol catabolism | Clostridioides, Clostridium, Geosporobacter, Lachnoclostridium |
BldR | butA | 2,3-Butanediol synthesis | Clostridium |
CelR | celCA-bglB-celB, celFB | Cellobiose catabolism | Alkaliphilus, Clostridium |
CitP | citA | Transporter | Alkaliphilus, Clostridium, Geosporobacter |
CrbR | crt-hbd-thl-maoC-bcd-etfAB, cotX-gntT | Butyrate/Butanol synthesis | Clostridium |
DhaQ | dhaKLM, ptsI | Dihydroxyacetone metabolism | Acetobacterium, Clostridium, Geosporobacter |
DioR | dpaL-pyrC-argE, tdcF, yqeB, pbuX, ygeW-ygfK-ssnA-ygeY, dioR, yqeC-ygfJ-yqeB-xdhC-hyp-fepDCB | Unknown | Clostridioides, Clostridium, Desulfotomaculum |
GamR | puuDT | Amino acid metabolism | Clostridioides, Clostridium, Romboutsia |
GasR | puuXP | Amino acid metabolism | Clostridium |
GfrR | gfrABCDEF | Glucosamine/fructosamine catabolism | Clostridioides, Clostridium |
HiaR | hiaL-hyp-hutH | Histidine catabolism | Clostridium |
CdsR | cdsB | Cysteine catabolism | Clostridium, Clostridioides |
LeuR | hadAIBC-acdB-etfBA | Leucine catabolism | Clostridioides |
LevR | levDEFG-sacC | Levan catabolism | Clostridium |
MdeR | mdeA-metT | Methionine catabolism | Clostridium |
MopR | mopR, mop, hyp-moeA | Unknown | Clostridium |
OrdR | ord-ortBA-oraSEF-orr-nhaC | Ornithine catabolism | Clostridioides, Clostridium, Geosporobacter, Romboutsia |
PrdR | prdABDEF, prdC | Proline catabolism | Alkaliphilus, Clostridioides, Clostridium, Geosporobacter |
SadR | sadh | Alcohol synthesis | Clostridium |
SarR | grdGF | Sarcosine metabolism | Clostridioides |
XanR | abfD-nifU-hyp-ach-golB, acp-caiC-luxEC | Butyrate/Butanol synthesis | Clostridium |
XcaA | thl | Unknown | Clostridium, Geosporobacter |
YcbP | phyL-uroD-eamA | Unknown | Dehalobacterium, Desulfosporosinus |
XcgR | cotY-gntT-bcd-etfAB | Butyrate/Butanol synthesis | Clostridium, Geosporobacter |
XcyR | malY-pepT-hyp | Peptide degradation | Clostridioides, Clostridium, Flavonifractor, Geosporobacter, Lachnoclostridium |
XduR | kdgT-uxaA | Pectin degradation | Alkaliphilus, Clostridioides, Clostridium, Geosporobacter |
XhaQ | rhaT | Transporter | Clostridioides |
XhpR | hyp-memP | Unknown | Desulfosporosinus, Carboxydocella, Desulfotomaculum |
XptB | sulT, hyp | Unknown | Dehalobacterium, Desulfitobacterium, Desulfosporosinus, Carboxydocella |
YctR | crt-gntT-caiB-bcd-etfAB | Butyrate/Butanol synthesis | Clostridioides |
YglR | hyp-gltD | Unknown | Clostridium |
YpdR | metM-memP-pepABC, fmdE-metM-hemABC | Peptide degradation | Clostridium |
YpyB | pdc-tdh-hyp | Unknown | Clostridium, Desulfosporosinus, Geosporobacter |
ZypR | tyrB-iorAB-butK | Amino acid metabolism | Clostridioides, Clostridium, Romboutsia |