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Table 8 KEGG analysis of selected WGCNA modules

From: Honey bee (Apis mellifera) larval pheromones may regulate gene expression related to foraging task specialization

Module

Trait association

Significantly enriched KEGG pathways (P < 0.05)

Significantly enriched GO categories (EASE <0.05)

10

BP, EBO, Forager-type

Metabolic pathways

Integral components of membrane, Fatty acid biosynthetic process

Carbon metabolism

Fatty acid metabolism

Peroxisome

7

BP alone

Glycerophospholipid metabolism

Ion channel

Neuroactive ligand-receptor interaction

Hippo signaling pathway

3

EBO alone

Pentose and glucuronate interconversions

Integral components of membrane

Metabolic pathways

FOXO signaling pathway

Neuroactive ligand-receptor interaction

Lysosome

Wnt signaling pathway

Dorso-ventral axis formation

Notch signaling pathway

Toll and Imd signaling pathway

AGE-RAGE signaling pathway in diabetic complications

  1. Module 10 was chosen based on its significant correlation with food and both brood pheromones, and modules 3 and 7 were selected based on their strong correlations with BP and EBO, respectively