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Fig. 4 | BMC Genomics

Fig. 4

From: NUCLIZE for quantifying epigenome: generating histone modification data at single-nucleosome resolution using genuine nucleosome positions

Fig. 4

The correlation of histone modification codes with gene expression. (a) Distributions of the numbers of the trivalent histone mark “T” and all codes at the upstream (up), downstream (down), and combined both upstream and downstream (total) surrounding TSS. (b) Correlation of gene expression levels (RPKM) with the number of single and multivalent histone marks within ±2 kb of the TSS for all genes in HepG2 cells. T, H3K4me3/H3K9ac/H3K27ac; D, H3K4me3/H3K9ac; A, H3K4me3. (c) The violin plot of the expression values of all genes in each cluster. Black dots, the median expression levels. (d) The correlation between gene expression values and numbers of the trivalent histone mark “T” and all codes at the upstream, downstream, and combined both upstream and downstream (total) surrounding TSS. Gene expression values and histone counts are median values from Fig. 4c and a, respectively

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BMC Genomics

ISSN: 1471-2164

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