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Fig. 5 | BMC Genomics

Fig. 5

From: Genome-wide mapping and profiling of γH2AX binding hotspots in response to different replication stress inducers

Fig. 5

Depletion of γH2AX at CGIs, TSSs and TTSs. a γH2AX binding at CGIs is significantly lower than expected by random, irrespective of fork stalling agents. Expected random γH2AX binding to CGIs is set to zero. p-values: permutation analysis. b Average genome-wide γH2AX binding at TSSs genome-wide to input shows local depletion compared to the surrounding 10 kb region. Red dotted line indicates the TSS position. c Average genome-wide γH2AX binding at TTSs to input compared to the surrounding 10 kb region. Red dotted line indicates the TTS position

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