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Table 8 Performance comparision on DIP and HPRD+BioGRID datasets

From: A seed-extended algorithm for detecting protein complexes based on density and modularity with topological structure and GO annotations

Data set

Algorithm

Number

CORUM complexes

CGPK complexes

   

JaccardI

JaccardS

Jaccard

JaccardI

JaccardS

Jaccard

DIP

MCODE

89

0.2585

0.0722

0.1129

0.2671

0.0546

0.0907

 

MCL

624

0.1725

0.1736

0.1731

0.1834

0.1356

0.1559

 

CFinder

992 2nd

0.3448 2nd

0.1883

0.2435 3rd

0.3269

0.1288

0.1848

 

DPClus

747

0.2275

0.1966

0.2109

0.2305

0.1418 3rd

0.1756

 

IPCA

904 3rd

0.3488 1 st

0.2005 3rd

0.2546 2nd

0.3455 1 st

0.1401

0.1994 2nd

 

CMC

358

0.3448 2nd

0.1881

0.2434

0.3383 2nd

0.1347

0.1926 3rd

 

COACH

389

0.2402

0.171

0.1998

0.2394

0.1234

0.1628

 

HC-PIN

229

0.0902

0.0571

0.07

0.1015

0.0478

0.065

 

SPICi

369

0.2364

0.1652

0.1945

0.246

0.1208

0.1621

 

ClusterONE

363

0.2696

0.135

0.1799

0.2694

0.1029

0.1489

 

WPNCA

535

0.2713

0.177

0.2143

0.2697

0.1306

0.176

 

CALM

1591 1 st

0.1665

0.2057 2nd

0.1841

0.1756

0.1569 2nd

0.1657

 

ClusterEPs

N/A

N/A

N/A

N/A

N/A

N/A

N/A

 

SE-DMTG

604

0.3383 3rd

0.2207 1 st

0.2672 1 st

0.3290 3rd

0.1584 1 st

0.2139 1 st

HPRD + BioGRID

MCODE

86

0.0969

0.0603

0.0743

0.1027

0.0587

0.0747

 

MCL

1094

0.0853

0.1806

0.1158

0.1032

0.1582

0.1249

 

CFinder

N/A

N/A

N/A

N/A

N/A

N/A

N/A

 

DPClus

1881

0.1943

0.2918

0.2332

0.2123

0.2442

0.2272

 

IPCA

9989 1 st

0.2463 2nd

0.3139 2nd

0.276 3rd

0.2548 2nd

0.2614

0.2581 3rd

 

CMC

N/A

N/A

N/A

N/A

N/A

N/A

N/A

 

COACH

4296 3rd

0.183

0.3114 3rd

0.2305

0.1933

0.2641 3rd

0.2232

 

HC-PIN

N/A

N/A

N/A

N/A

N/A

N/A

N/A

 

SPICi

1100

0.171

0.2119

0.1893

0.1944

0.1829

0.1885

 

ClusterONE

1763

0.145

0.2166

0.1737

0.1811

0.1932

0.1869

 

WPNCA

2750

0.2251 3rd

0.3120

0.2615 2nd

0.2462 3rd

0.2687 2nd

0.2570 3rd

 

CALM

7810 2nd

0.0283

0.2456

0.0507

0.0348

0.2001

0.0593

 

ClusterEPs

N/A

N/A

N/A

N/A

N/A

N/A

N/A

 

SE-DMTG

2773

0.4409 1 st

0.4046 1 st

0.422 1 st

0.467 1 st

0.3258 1 st

0.3838 1 st

  1. CORUM complexes and CGPK complexes are used as standard complexes.
  2. NOTE: The highest value in each row is shown in bold. N/A means that we fails to obtain the results under given program or software