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Table 2 Top 10 differentially methylated CpG sites and their associated genes in E. coli 3 hpc and E. coli 24 hpc compared to control

From: DNA methylation analysis of porcine mammary epithelial cells reveals differentially methylated loci associated with immune response against Escherichia coli challenge

CpG site

Chr

Strand

Gene name

P value

Distance to gene feature (TSS ± bp)

Islands/shore

E. coli vs Control

 cg5322871

5

+

EFCAB6

2.64E-05

− 58243

 

 cg97042458

4

–

FLG2

5.15E-05

59383

cpg island

 cg51707353

14

–

 

1.46E-04

− 16765

 

 cg605583

4

–

CYC1

1.69E-04

3413

 

 cg22964888

16

+

GDNF

2.10E-04

931

cpg island

 cg3759161

3

–

SF21

2.22E-04

16920

 

 cg95955381

15

+

MYO1B

2.23E-04

47142

 

 cg76083105

2

–

GNG7

2.36E-04

28337

 

 cg68450973

16

–

LARP1

2.92E-04

33945

cpg island

 cg190005969

1

–

SLC38A6

3.20E-04

81855

 

E. coli vs Control

 cg24937951

10

+

CYB5R1

1.97E-10

− 6265

 

 cg77052099

11

+

COL4A2

6.26E-06

54975

 

 cg63545568

6

–

SDF4

3.78E-05

− 782

 

 cg54274409

12

–

NTN1

4.06E-05

− 32552

cpg shore

 cg3518148

12

–

DNAH17

4.98E-05

32968

cpg island

 cg727575

8

–

 

6.54E-05

68814

cpg island

 cg3323937

6

–

GSE1

7.58E-05

26142

 

 cg33280374

9

+

MMP20

8.26E-05

27673

 

 cg123320105

4

+

ABCA4

8.94E-05

− 51088

 

 cg6288374

2

–

SF3B2

1.04E-04

5221

cpg island