Fig. 1

Volcanoplot (a) and KEGG pathway (b) of differentially expressed genes in the Drosophila melanogaster ovary due to the infection of Wolbachia. (a) Distribution of the relative expression of genes in the infected versus uninfected fly ovaries. Green dots represent downregulated genes; red dots represent upregulated genes and blue dots represent unchanged genes. (b) The 20 most enriched KEGG pathways based on the differentially expressed genes in the presence of Wolbachia. The x-axis shows the rich factor; the y-axis shows the pathway names. The size of each point represents the number of genes enriched in a particular pathway. The larger the rich factor and the smaller the q-value, the more significant the degree of enrichment. Dmel T: Drosophila melanogaster treated with tetracycline (without Wolbachia); Dmel wMel: Drosophila melanogaster infected with wMel Wolbachia