Fig. 5

Expression pattern of commonly expressed genes identified between the T1 strain and the Cp13 mutant. Hierarchical clustering of the 25 DEGs commonly expressed between the strains was used to identify the pattern of expression of these genes. Rlog-transformed normalized counts in the heatmap were clustered based on Euclidean distance and show 25 DEGs consistently up- or down-regulated in the T1 strain and Cp13 mutant. Columns represent sample identification in relation to experimental condition and strains. Representative gene clusters identified between both strains are indicated highlighting the clusters involving high-affinity hemin-binding acquisition systems, transcription factors and genes encoding the cytochrome bcc-aa3 super complex of the respiratory chain. Up-regulated genes are shown as green arrows; down-regulated genes are shown as red arrows and genes with unchanged expression are shown as gray. Black solid bars represent DtxR predicted regulatory binding sites and striped-bars represent GlxR regulatory binding sites