Fig. 4

Transcriptional responses to cadmium treatment. a, numbers of up- and down-regulated genes in each species after 3-h and 24-h exposures to the species-specific LC10. b, GO terms enriched in the transcripts up-regulated under cadmium treatment. The full list of DE genes and the corresponding fold change and p-values are available from Additional file 3. c, GO terms enriched in the transcripts down-regulated under these conditions. Only GO terms enriched with a p-value of at most 0.001 and including at least two differentially expressed transcripts are shown. Only GO terms enriched with a p-value <0.001 and including at least two differentially expressed transcripts are shown. d, summary of expression for the two most abundant MT-like transcripts. The p-values shown on top of the boxplots come from the DESeq2 analysis, except for the value in parentheses calculated with the Mann-Whitney test