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Table 4 Ovodefensin peptides predicted in the Komodo dragon genome

From: The Komodo dragon (Varanus komodoensis) genome and identification of innate immunity genes and clusters

Name

Closest Anole Ortholog

Closest Snake Ortholog

Sequences

Scaffold 210 Ovodefensins

This scaffold contains the cluster of six β-ovodefensin genes, one intercluster β defensin, and 15 β-defensin genes that are similar to anole lizard β-defensins. The cluster begins with the CTSB gene. These genes include large β defensins.

VkOVOD1_VARKO

LzOVOD1

 

GM*PPHLCFLAMTLHLACSFCGMNFCAGAPRKLWCYCAAQRCCAL

VkOVOD2_VARKO

 

SnOVOD1

GRRRASDTQSCIRREGYCKPQCNETGPVPELNLGTCTNRQQKCCRPQEL

VkOVOD3_VARKO

 

SnOVOD2

GCKGHRSCSSLGGRCAKSCKSLGSGYTAYHTCDCARSGLQCCVPHKKG

VkOVOD4_VARKO

LzOVOD14

SnOVOD3

GYRQHCSSYCHGFCSSKCPQHKVAQANCACALYGGICCVS

VkOVOD5_VARKO

  

GLRDWGSEALLCSGSAPISTADFRRWCWGTLALCHGSYAMEYRRGPFCPPCCL

VkOVOD6_VARKO

 

SnOVOD5

RHCNTYCYGQCLKSCPYGWVPTSNCACQHTSNICCLPP

  1. Reptile ovodefensin orthologs are also indicated (where they exist) as well as the ovodefensin peptide sequences encoded by each gene
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BMC Genomics

ISSN: 1471-2164

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