Table 1 Matrix generation and visualization functionality of six commonly used tools. M corresponds to providing functionality to only generate a mutational matrix; MP corresponds to providing functionality to both generate and plot a mutational matrix. * indicates that a tool can perform only one of the actions in a single run; for example, Helmsman can either generate a 96 or a 1536 mutational matrix but not both in a single run

From: SigProfilerMatrixGenerator: a tool for visualizing and exploring patterns of small mutational events