Table 2 Top 5% functional annotation of upregulated genes of the embryos on Day 12
Category description | Gene Counts | Fold Enrichment | FDR | P Value |
|---|---|---|---|---|
Prostatic bud formation | 7 | 7.82 | 0.12 | 0.0001 |
Metalloendopeptidase inhibitor activity | 10 | 6.21 | 0.01 | 0.0000 |
Chemorepellent activity | 14 | 5.15 | 0.00 | 0.0000 |
Lateral sprouting from an epithelium | 8 | 6.70 | 0.10 | 0.0000 |
Collagen-activated signaling pathway | 6 | 7.54 | 0.84 | 0.0004 |
Glomerulus vasculature development | 12 | 5.24 | 0.01 | 0.0000 |
Laminin complex | 6 | 7.16 | 0.82 | 0.0005 |
Cardiac septum morphogenesis | 25 | 3.99 | 0.00 | 0.0000 |
Positive regulation of extracellular matrix organization | 10 | 5.58 | 0.04 | 0.0000 |
Negative chemotaxis | 17 | 4.17 | 0.00 | 0.0000 |
Morphogenesis of an epithelial bud | 8 | 6.18 | 0.19 | 0.0001 |
Glomerulus development | 24 | 3.83 | 0.00 | 0.0000 |
Creatine metabolic process | 7 | 6.39 | 0.57 | 0.0003 |
Cardiac septum development | 34 | 3.56 | 0.00 | 0.0000 |
Positive regulation of epithelial cell migration | 37 | 3.54 | 0.00 | 0.0000 |
Ventricular septum development | 22 | 3.51 | 0.00 | 0.0000 |
Renal system vasculature development | 12 | 4.82 | 0.02 | 0.0000 |
Kidney vasculature development | 12 | 4.82 | 0.02 | 0.0000 |
Kidney morphogenesis | 32 | 3.42 | 0.00 | 0.0000 |
Basement membrane | 34 | 3.42 | 0.00 | 0.0000 |
Nephron development | 46 | 3.35 | 0.00 | 0.0000 |
Cardiac chamber morphogenesis | 39 | 3.32 | 0.00 | 0.0000 |
Renal tubule development | 31 | 3.28 | 0.00 | 0.0000 |
Nephron tubule development | 30 | 3.28 | 0.00 | 0.0000 |
Renal tubule morphogenesis | 25 | 3.26 | 0.00 | 0.0000 |
Nephron morphogenesis | 25 | 3.22 | 0.00 | 0.0000 |
Embryonic skeletal joint development | 8 | 5.74 | 0.35 | 0.0002 |
Positive regulation of ossification | 27 | 3.19 | 0.00 | 0.0000 |
Mesonephros development | 32 | 3.12 | 0.00 | 0.0000 |
Smooth muscle cell migration | 20 | 3.53 | 0.00 | 0.0000 |
Ureteric bud development | 30 | 3.11 | 0.00 | 0.0000 |
Extracellular matrix disassembly | 27 | 3.08 | 0.00 | 0.0000 |
Mesonephric epithelium development | 30 | 3.08 | 0.00 | 0.0000 |
Mesonephric tubule development | 30 | 3.08 | 0.00 | 0.0000 |
Cardiac chamber development | 47 | 3.05 | 0.00 | 0.0000 |
Kidney epithelium development | 43 | 3.02 | 0.00 | 0.0000 |
Nephron epithelium morphogenesis | 24 | 3.17 | 0.00 | 0.0000 |