TY - JOUR AU - Sigalova, Olga M. AU - Chaplin, Andrei V. AU - Bochkareva, Olga O. AU - Shelyakin, Pavel V. AU - Filaretov, Vsevolod A. AU - Akkuratov, Evgeny E. AU - Burskaia, Valentina AU - Gelfand, Mikhail S. PY - 2019 DA - 2019/09/12 TI - Chlamydia pan-genomic analysis reveals balance between host adaptation and selective pressure to genome reduction JO - BMC Genomics SP - 710 VL - 20 IS - 1 AB - Chlamydia are ancient intracellular pathogens with reduced, though strikingly conserved genome. Despite their parasitic lifestyle and isolated intracellular environment, these bacteria managed to avoid accumulation of deleterious mutations leading to subsequent genome degradation characteristic for many parasitic bacteria. SN - 1471-2164 UR - https://doi.org/10.1186/s12864-019-6059-5 DO - 10.1186/s12864-019-6059-5 ID - Sigalova2019 ER -