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Fig. 2 | BMC Genomics

Fig. 2

From: A qualitative transcriptional signature for the histological reclassification of lung squamous cell carcinomas and adenocarcinomas

Fig. 2

Immunohistochemical analysis of Krt5 protein and Agr2 protein expressions in human lung cancer tissue microarray. a Krt5 and Agr2 proteins expression profile in lung cancer tissue array. The red frame containing samples from A1-E8 are pSCC. The green frame containing samples from E18-K5 are pADC. The remaining samples are the other subtypes of lung cancer and normal controls. b, c Inverse correlation between Krt5 protein and Agr2 protein expressions in pADC (b) and pSCC (c) samples. The protein expression score was quantified and considered as low, medium and high expression, basing on a multiplicative index of the average staining intensity and the extent of staining (see Methods). d, e Representative immunohistochemical staining results of Krt5 and Agr2 proteins in pADC (d) and pSCC (e) samples. Scale bar, 1 mm

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