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Fig. 5 | BMC Genomics

Fig. 5

From: A qualitative transcriptional signature for the histological reclassification of lung squamous cell carcinomas and adenocarcinomas

Fig. 5

The validation of the reclassifications by the signature for small biopsy and poorly differentiated specimens. a The violin plot of proliferation scores and b mRNA expressions of the subtype-specific marker genes in the GSE58661 dataset derived from small biopsy specimens. c The violin plot of proliferation scores of 23 poorly differentiated specimens in the GSE94601 dataset. d The volcano plot of the differential expressions of the 44 proliferation-related genes in the pSCC samples reclassified as ADC when compared with the signature-confirmed pSCC samples. For the 44 proliferation-related genes, 20 genes were significantly differentially expressed and all the genes were down-regulated in the reclassified pSCC

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