Fig. 5From: Α de novo 3.8-Mb inversion affecting the EDA and XIST genes in a heterozygous female calf with generalized hypohidrotic ectodermal dysplasiaEDA isoforms and protein domains. Note that EDA-A1 and EDA-A2 are not separated since they only differ by two amino-acids in exon 8. Both of these isoforms possess a membrane form and a secreted form after cleavage by furine at position 159–160 (exon 2)Back to article page