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Fig. 2 | BMC Genomics

Fig. 2

From: 7C: Computational Chromosome Conformation Capture by Correlation of ChIP-seq at CTCF motifs

Fig. 2

ChIP-seq similarity and genomic features of looping and non-looping CTCF motif pairs. a Boxplot of Pearson correlation coefficients of ChIP-seq signals between CTCF motif pairs for all CTCF motif pairs within 1 Mb genome-wide. The correlation is shown separately for non-looping and looping motif pairs (according to HI-C and ChIA-PET data in GM12878 cells), and for six selected ChIP-seq data sets in GM12878 cells. b Distance distribution between looping (green) and non-looping CTCF motif pairs. c Percent of looping and non-looping CTCF motif pairs in convergent, divergent, both forward, or both reverse orientation. d Distribution of CTCF motif hit significance as -log10 transformed p-value for looping and non-looping CTCF motif pairs. For each motif pair only the less significant motif is considered

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