Fig. 7
PrrAB regulates oxidative phosphorylation genes and ATP levels in M. smegmatis. a Heatmap of genes participating in oxidative phosphorylation. Color bar indicates log2 fold change of gene expression between mc2155 vs. FDL10 (left column) and FDL15 vs. FDL10 (right column). M. smegmatis genes significantly regulated are denoted by asterisks (*, p < 0.05; **, q < 0.05) in at least one group comparison. b M. smegmatis viability (CFU/ml) at harvest and (c) corresponding ATP levels (pM/CFU) normalized to mc2155 were measured from exponentially-growing (OD600 ~ 0.6) aerobic cultures in M7H9 broth. ****, p < 0.0001; one-way ANOVA, Dunnett’s multiple comparisons