Insight into genetic regulation of miRNA in mouse brain

BMC Genomics

Table 5 miRNA associated with ethanol related phenotypes

miRNA	phenotype	Rho	FDR	bQTL chr	bQTL location (Mb)	bQTL p-value
novel:chr4_11381	ST Saline	−0.415	0.061	4	87.1	0.018
mmu-miR-32-3p	ST Saline	0.349	0.170	1	171.8	0.318
mmu-miR-208b-3p	AFT Ethanol	0.338	0.193	14	54.7	0.189
novel:chr4_10452	AFT Ethanol	0.343	0.193	9	100.3	0.206

Spearman correlation was used to determine associations. bQTL analysis was performed on the mi-eQTL locations of those miRNA associated with an ethanol related phenotype. ST Saline is the sleep time phenotype measured on mice pre-treated with saline. AFT Ethanol is the acute functional tolerance phenotype measured on mice pre-treated with ethanol. FDR is the false discovery rate. Only associations with FDR < 0.2 are shown

ISSN: 1471-2164