Fig. 1

Hybrid dynamics throughout Aspergilli. (A) Maximum Likelihood (ML) phylogeny of PKS-NRPS and NRPS-PKS hybrid proteins was created on aligned and trimmed protein sequences. Branches shown in grey (A-E) are shown in Additional file 9: Figure S1, Additional file 10: Figure S2, Additional file 11: Figure S3, Additional file 12: Figure S4, Additional file 13: Figure S5. Sections and species groups are indicated by tip color; the orientation of hybrids N-type (NRPS-PKS) and P-type (PKS-NRPS) is indicated by tip shape. Percentage of 1000 times bootstrap values (red) are indicated for major branches, the remaining values are shown in Additional file 9: Figure S1, Additional file 10: Figure S2, Additional file 11: Figure S3, Additional file 12: Figure S4, Additional file 13: Figure S5. The phylogenetic tree is available as Additional file 1. (B) Unrooted view of the phylogenetic tree shown in A. Tip colors indicate sections. Branches highlighted in A are marked in B. (C) Classification of nearest neighbors of ML phylogeny. A matrix of tip distances was extracted from the tree and nearest neighbors classified according to their section, thus the barplot shows the origin of hybrid genes by a species. The background color indicates the section of Aspergillus species while the bar color indicates the section of the nearest neighbor hybrid ortholog