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Table 2 Genes overexpressed in livers of mature hens, that are predicted to be secreted and whose protein products have been identified in egg yolk and/or vitelline membrane. EY, egg yolk; VM, vitelline membrane [13,14,15]. ML/IL ratio: ratio of gene expression in the liver of 38-week laying hens (ML) to the expression in the liver of 10-week juvenile pullets (IL)

From: Integrative analysis of transcriptomic data related to the liver of laying hens: from physiological basics to newly identified functions

Name [Gallus gallus]

Gene Symbol/ID

Localization

Ratio ML/IML

Subcellular location

riboflavin-binding protein

RBP/396449

EY;VM

66.92

Secreted

vitellogenin-3

VTG3/424534

EY;VM

45.88

Secreted

apovitellenin-1

APOV/396476

EY;VM

42.37

Secreted

cathepsin E-A-like

CSTEAL/417848

EY;VM

34.85

Secreted

vitellogenin-1

VTG1/424547

EY;VM

33.79

Secreted

WAP four-disulfide core domain 8

WFDC8/419301

EY

20.87

Secreted

zona pellucida sperm-binding protein 1

ZP1/395418

EY;VM

15.05

Secreted

avidin-related protein 6-like

LOC426220/426220

EY;VM

10.48

Secreted

lactadherin

MFGE8/415494

EY;VM

5.75

Secreted

transcobalamin-2

TCN2/429737

EY

5.47

Secreted

apolipoprotein B

APOB/396535

EY;VM

5.13

Secreted

ovochymase-1

OVCH1/769290

VM

4.01

Secreted

nidogen-1

NID1/395531

EY

2.77

Secreted

uncharacterized protein LOC421956

LINC00954/421956

VM

2.97

Secreted

fibulin-1

FBLN1/373979

EY

2.35

Secreted

thrombospondin-2

THBS2/414837

VM

1.53

Secreted

ceruloplasmin

CP/771940

EY

1.50

Secreted

vitamin D-binding protein

GC/395696

EY

1.48

Secreted