Fig. 1

Phylogeny and distribution of host-adaptation genes for 31 B. cenocepacia strains. The evolutionary distances were computed using the Maximum Composite Likelihood method. A total of 1057 conserved core-genes, totaling 1,039,265 positions were used in the final dataset. Branch label colors are indicative of the isolation source of the respective strains. These can either be clinic (red), rhizospheric (green) or environmental (grey). The colored shapes indicate the presence of genetic elements in the genomes of the corresponding strains. Squares correspond to genes that were found to be preferably enriched in clinical (vir.) or environmental (env.) species. From left to right: cable pilus (cblA), 22 kDa adhesion (adhA), Burkholderia cenocepacia epidemic strain marker (BCESM), transcriptional regulator kdgR, bile acid 7-alpha dehydratase (baiE), taurine dehydrogenase (tauX), sulfoacetaldehyde acetyltransferase (xsc), tellurite resistance cluster (telA), low oxygen activated locus (lxa), respiratory nitrate reductase cluster (narIJHGK), nitrate sensor and regulation cluster (narLX), lectin like bacteriocin 88 (llpA), nitrile hydratase cluster (nthAB), phenylacetaldoxime dehydratase (oxd), feruloyl-esterase (faeB), pyrrolnitrin biosynthesis cluster (prn), galacturonate metabolism genes (uxaAB). Circles indicate the presence of the pC3 megaplasmid and the afc cluster. This figure was generated using iTOL [48]